Gene information
Official symbol TNC
Official full name tenascin C
Gene type protein-coding gene
Chromosome9q33.1
Alias symbolTN; MGC167029
Previous symbolHXB; DFNA56
Gene familyTenascins
Resources
Entrez Gene 3371
HGNC HGNC:5318
Ensembl ENSG00000041982
Vega OTTHUMG00000021010
UCSC uc004bjj.6
GO terms: 35 records
GO Description Category LogP Number of genes Detail
GO:0001503 ossification GO Biological Processes -16.3087139 28 More
GO:0001558 regulation of cell growth GO Biological Processes -19.1123936 65 More
GO:0001649 osteoblast differentiation GO Biological Processes -6.81659337 21 More
GO:0001655 urogenital system development GO Biological Processes -19.5104956 58 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0005198 structural molecule activity GO Molecular Functions -7.51921139 30 More
GO:0005201 extracellular matrix structural constituent GO Molecular Functions -12.8379048 20 More
GO:0005604 basement membrane GO Cellular Components -9.30297759 21 More
GO:0005788 endoplasmic reticulum lumen GO Cellular Components -47.2996164 57 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0022612 gland morphogenesis GO Biological Processes -7.35048069 19 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030312 external encapsulating structure GO Cellular Components -73.3689453 93 More
GO:0030850 prostate gland development GO Biological Processes -4.21089449 9 More
GO:0031012 extracellular matrix GO Cellular Components -73.4416071 93 More
GO:0031099 regeneration GO Biological Processes -17.4553316 23 More
GO:0031102 neuron projection regeneration GO Biological Processes -2.11862029 3 More
GO:0031175 neuron projection development GO Biological Processes -7.36986002 58 More
GO:0031347 regulation of defense response GO Biological Processes -64.5971043 148 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0043394 proteoglycan binding GO Molecular Functions -12.1259478 11 More
GO:0048608 reproductive structure development GO Biological Processes -16.4007448 61 More
GO:0048678 response to axon injury GO Biological Processes -4.04506120 6 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0048732 gland development GO Biological Processes -26.3979320 74 More
GO:0050727 regulation of inflammatory response GO Biological Processes -68.5964592 121 More
GO:0050808 synapse organization GO Biological Processes -6.17744712 32 More
GO:0060512 prostate gland morphogenesis GO Biological Processes -4.25041921 7 More
GO:0060740 prostate gland epithelium morphogenesis GO Biological Processes -4.51081372 7 More
GO:0061458 reproductive system development GO Biological Processes -16.2516665 61 More
GO:0062023 collagen-containing extracellular matrix GO Cellular Components -67.6170082 80 More
GO:0098636 protein complex involved in cell adhesion GO Cellular Components -5.90313372 12 More
KEGG pathways: 4 records
KEGG Description Category LogP Number of genes Detail
hsa04151 PI3K-Akt signaling pathway KEGG Pathway -29.3006421 73 More
hsa04510 Focal adhesion KEGG Pathway -16.5268196 41 More
hsa04512 ECM-receptor interaction KEGG Pathway -16.8587083 28 More
hsa05165 Human papillomavirus infection KEGG Pathway -8.63301470 40 More
Drug-Gene interaction
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Related drugs: 5 records
Related studies: 5 records
Molecular factor Omics type Application Objective MI type Reference
tenascin proteomics medium predictor major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Sato A et al. J Am Coll Cardiol. 2006
tenascin proteomics good predictor left ventricular remodeling[prognosis (bad)] acute myocardial infarction Sato A et al. J Am Coll Cardiol. 2006
tenascin proteomics coronary artery stenosis[prognosis (bad)] acute anterior myocardial infarction Celik A. J Atheroscler Thromb. 2011
tenascin proteomics cardiovascular adverse events[prognosis (bad)] acute ST elevation myocardial infarction Sato A et al. J Card Fail. 2012
tenascin proteomics excellent predictor reperfusion failure[prognosis (bad)] acute anterior ST elevation myocardial infarction Arican Ozluk O et al. Int J Clin Exp Med. 2015
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